I set up Amazon smile today so that a percentage of what I purchase through amazon will go to a non-profit I select. I chose Team Rubicon; their facebook post turned me onto amazon smile.
I do tend to buy a lot of things from Amazon. I buy a lot of things online because I don't really like shopping and don't really need many things and when I do need something I want something particular.
I installed the extensions to my browser so I don't have to do anything to make my Amazon purchases donate.